Clive Wearing, a renowned conductor and music producer, suffers from a severe case of amnesia after contracting a virus in 1985 that destroyed parts of his brain. With a memory span of only a few seconds, he lives in a constant state of the present, unable to retain new information or recall his past. Despite his condition, his musical ability remains intact, and his wife, Deborah, remains his constant companion, navigating the challenges of his life and their relationship as they both struggle to find meaning in a world where his memory is constantly being wiped clean.